SMC | Optimising Seasonal Malaria Chemoprevention in West and Central Africa

8th SMC Alliance Annual Review: Key takeaways

World Malaria Day 2025

_{Malaria ends with us: reinvest, reimagine, reignite}

Photo: Toby Madden / MMV

Global health

Optimizing seasonal malaria chemoprevention

Photo: Toby Madden / MMV

Photo: Toby Madden / MMV

SMC is to be implemented in areas where malaria is highly seasonal, and transmission is intense.

Photo: Toby Madden / MMV

Seasonal Malaria Chemoprevention (SMC) is the intermittent administration of full treatment of an anti-malarial medicine during the malaria season to prevent malarial illness.

1

Featured Resources

SMC Alliance Annual Meeting Report 2025

SMC Alliance Learnings Report April 2025

SMC Alliance 2025 Annual Meeting (Lomé) Presentations

WHO guidelines for malaria, 30 November 2024

World Health Organization

1

News

The Federal Government calls on African parliamentarians to expedite actions toward increasing budgetary allocations for Seasonal Malaria Chemoprevention (SMC)

African parliamentarians to expedite actions toward increasing budgetary allocations for SMC

Say it is a key strategy in reducing under-five mortality.

African leaders during COPEMA Dinner on the sidelines of RBM Partnership to End Malaria The Big Push 2025

African leaders unite in Abuja to champion domestic investment in malaria chemoprevention

Global Fund Procurement Boosts SMC Supply with 7 Million Doses of Life-Saving Antimalarial Treatment

View all News & Events

1

Resources

Status and prospects of seasonal malaria chemoprevention among children in Sahelian countries: A systematic review and meta-analysis

PLOS Global Public Health

Peer-reviewed article

Effectiveness of sulfadoxine-pyrimethamine plus amodiaquine and dihydroartemisinin-piperaquine for seasonal malaria chemoprevention in Uganda: a three-arm, open-label, non-inferiority and superiority, cluster-randomised, controlled trial

The Lancet Infectious Disease

Peer-reviewed article

Expanding seasonal malaria chemoprevention beyond the Sahel region

The Lancet Infectious Disease

Peer-reviewed article

Seasonal malaria chemoprevention in northern Mozambique: a cost-effectiveness analysis

Malaria Journal

Peer-reviewed article

View all resources