SMC | Optimising Seasonal Malaria Chemoprevention in West and Central Africa

Joint annual meetings of the SMC Alliance and the Alliance for Malaria Prevention (AMP) to advance global partnerships to fight malaria.

Photo: Toby Madden/MMV

World malaria report 2025

Addressing the threat of antimalarial drug resistance

Photo: Toby Madden / MMV

Global health

Optimizing seasonal malaria chemoprevention

Photo: Toby Madden / MMV

Photo: Toby Madden / MMV

SMC is to be implemented in areas where malaria is highly seasonal, and transmission is intense.

Photo: Toby Madden / MMV

Seasonal Malaria Chemoprevention (SMC) is the intermittent administration of full treatment of an anti-malarial medicine during the malaria season to prevent malarial illness.

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Featured Resources

SMC Alliance Annual Meeting Report 2025

SMC Alliance Learnings Report April 2025

SMC Alliance 2025 Annual Meeting (Lomé) Presentations

WHO guidelines for malaria, 30 November 2024

World Health Organization

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News

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Resources

Agent-based simulation of seasonal malaria chemoprevention strategy in Southern Tanzania: comparing dihydroartemisinin-piperaquine with or without primaquine

Malaria Journal

Peer-reviewed article

Malaria: a review on its current epidemiological status and management strategies

Malaria Journal

Peer-reviewed article

Indirect benefits of seasonal malaria chemoprevention for non-malarial pediatric infections and routine antibiotic use in real-world programmatic settings: a pre-post study using positive and negative controls

BMC Infectious Diseases

Peer-reviewed article

Effectiveness of antenatal care delivery of intermittent preventive treatment in pregnancy with sulfadoxine-pyrimethamine in the context of an integrated strategy with seasonal malaria chemoprevention in Mali and Burkina Faso

BMJ Global Health

Peer-reviewed article

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